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最新資訊

第一屆亞太地區果蠅研究研討會 -2011/5/22~25

Asia-Pacific Drosophila research conference (APDRC)

網站連結

白麗美(Li-Mei Pai)
長庚大學生化科 副教授
Email:pai@mail.cgu.edu.tw
Phone:(03)2118800#5520
Fax:(03)2118065

學經歷

● 博士後研究 Princeton University HHMI-Department of Molecular Biology (1997)
● 博士 University of North Carolina at Chapel Hill-Department of Biology (1992)
● 碩士 陽明大學微生物暨免疫研究所 (1989)
● 學士 東吳大學微生物系 (1987)

發表論文

1. Pei-Yu Wang and Li-Mei Pai. (2011) D-Cbl binding to Drk leads to dose-dependent down-regulation of EGFR signaling and increases receptor-ligand endocytosis. PLoSONE. 6(2) e17097. SCI
2. Tzer-En Nee, Jen-Cheng Wang, Pei-Yu Wang, Ruo-Rung Huang, Wei-Chieh Lin, Chia-Hui Fang, and Li-Mei Pai. (2011) Lie group study of Raman spectra of the Gurken gradient in Drosophila oogenesis. Anal. Bioanal. Chem. In press. SCI
3. Sun, N.K., Sun, C.L., Lin, C.H., Pai L.M., Chao, C.C.(2010) Damaged DNA-binding protein 2 (DDB2) protects against UV irradiation in human cells and Drosophila. Journal of Biomedical Science,17, 27.(SCI)
4. Liao C.H., Yeh S.C., Huang Y.H., Chen R.N., Tsai M.M., Chen W.J., Chi H.C., Tai P.J., Liao C.J., Wu S.M., Cheng W.L., Pai L.M., Lin K.H.(2010) Positive regulation of spondin 2 by thyroid hormone is associated with cell migration and invasion. Endocrine-Related Cancer. 17(1):99-111 .(SCI)
5. Cheng J.C., Yeh Y.J., Pai L.M., Chang M.L. and Yeh C.T.(2009) 293 Cells Over-expressing Human ADI1 and CD81 are Permissive for Serum-derived Hepatitis C Virus Infection. Journal of Medical Virology. Journal of Medical Virology, 81, 1560-1568. (SCI)
6. Chen L.S., Wei P.C., LiuT., Kao C.H., Pai L.M. and Lee C.K. (2009) STAT2 hypomorphic mutant mice display impaired dendritic cell development and antiviral response. J. Biol. Sci. 16,22.(SCI)
7. Chang W. L., Liou Willisa, Pen H.C., Chou H.Y., Chang Y.W., Li W.H., Chiang W. and Pai L.M. (2008) The gradient of Gurken, a long range morphogen, is directly regulated by Cbl-mediated endocytosis. Development. 135, 1923-1933.
8. Wang P.Y., Chang W. L. and Pai L.M. (2008) Smiling Gurken gradient. Fly, 2:3, 1-3.
9. Pai L.M., Wang P.Y., Chen S.R., Barcelo G., Chang W.L., Nilson L. and Schupbach T. (2006) Differential effects of Cbl isoforms on Egfr signaling in Drosophila. Mechanisms of Development. 123, 450-462.
Before
1 Pai L.M., Barcelo G. and Schüpbach T. (2000) D-cbl, a negative regulator of the Egfr pathway, is required for dorsoventral patterning in Drosophila oogenesis. Cell. 103, 51-61.
2. Cox R.T., Pai L.M., Kirkpatrick C., Stein J. and Peifer M. (1999) Roles of the C Terminus of Armadillo in Wingless signaling in Drosophila. Genetics. 153, 319-332.
3. Cox R. T., Pai L.M., Miller J.R., Orsulic S., Stein J., McCormick C.A., Audeh Y., Wang W., Moon R.T., Peifer M. (1999) Membrane-tethered Drosophila Armadillo cannot transduce Wingless signal on its own. Development. 126, 1327-1335.
4. Pai L.M., Orsulic S., Bejsovec A. and Peifer M. (1997) Negative regulation of Armadillo, a Wingless effector in Drosophila. Development. 124, 2255-2266.
5. Pai L.M., Kirkpatrick C., Blanton J., Oda H., Takeichi M. and Peifer M. (1996) Drosophila α-catenin and E-cadherin bind to distinct regions of Drosophila Armadillo. J. Biol.Chem. 271, 32411-32420.