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| All 20 common amino acids arise from a few intermediates in the central metabolic pathways. |
| These common intermediates include oxaloacetate, pyruvate, a-ketoglutarate, glycerate-3-P, erythrose-4-P and PRPP. |
| The rates of synthesis for all amino acids are regulated according to the amount needed. (NOT by the amount of substrate or precursors) |
| The flow is regulated mostly by end-product inhibition. Amino acid (end product) inhibits the first enzyme in the pathway for its synthesis. |