Metabolism of amino acids (I)
Amino acid biosynthesis and nitrogen fixation
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Amino acids are the building blocks of proteins.
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Amino acids also serve as precursors to many important small biologically
active compounds, such as nucleotides, porphyrins, lipids, and co-enzymes.
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Amino acids are also used to convert nitrogen and sulfur from inorganic
to organic forms.
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Amino acids are involved in the regeneration of ATP to be used as energy.
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During the biosynthesis and degradation of amino acids, the nitrogen and
carbon molecules can be better considered separately.
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The carbon molecules of most amino acid are derived from (during biosynthesis)
or entered into (during degradation) the central metabolic pathways.
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The first step in amino acid metabolism usually involves either addition
(during biosynthesis) or removal (during degradation) of the a amino group.
Subjects to be covered
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Pathways to amino acid biosynthesis and their links
to central metabolic pathways.
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Understanding of amnio acid biosynthesis pathways.
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Amino acid Glutamate and nitrogen fixation.
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Amino acid serine and sulfur fixation.
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Biosynthesis of branched chain amino acids.
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Biosynthesis of aromatic amino acids.
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Biosynthesis of amino acid histidine.
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Amino acids that are not found in proteins.
II
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